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What is Serrapeptase?

By on Oct 17, 2013

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as a dietary supplement, serrapeptase is becoming much more popular, but what is all the fuss about? This enzyme was initially discovered by the German scientist Hans Nieper over 20 years ago. Serrapeptase has been promoted to treat many health conditions.

What is Serrapeptase?

This enzyme was originally found in the intestines of the silkworm, but is now prepared synthetically in the lab through the fermentation process. It is main action is a strong anti-inflammatory response, without gastrointestinal side effects of conventional NSAID’s (non steroidal anti-inflammatory) drugs such as ibuprofen, naproxen and diclofenac. Serrapeptase is thought to work by helping the body to break down protein.

Hans Nieper used this supplement to treat clogged arteries in his patients. The scientist also reported that Serrapeptase dissolved blood clots and reduced varicose veins.

Other potential uses of Serrapeptase:

  • Sinusitis
  • Sore throats
  • Ulcerative colitis
  • Crohns disease
  • Osteoporosis
  • Back pain
  • Osteoarthritis
  • Migraines

 It must be stated that more studies are required to back up these potential uses of this supplement.


The long term safety of Serrapeptase has not yet been determined, but short term treatment of up to 3-4 weeks seems to be ok. It is best avoided in pregnancy and if breast feeding, as there is not enough information regarding safety.

There is also a potential interaction with medications that help to prevent blood clots such as anticoagulants (e.g. warfarin) and anti-platelet drugs (e.g. aspirin and clopidrogel). If you are taking these medications, it is best to avoid this supplement.

The recommended dosage for Serrapeptase ranges from 10mg (20,000 units) to 60 mg (120,000 units) three times a day on an empty stomach (one hour before meals or 2 hours after a meal).


Please consult with your pharmacist or nutritionist before starting this supplement.